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Trial to Reduce Insulin dependent diabetes in the Genetically at Risk

Join Dr. Dorothy Becker for a special chat about the TRIGR study. The chat will be held on Tuesday, January 20, 2004 at 9pm Eastern in the TRIGR chat room.

Type 1 diabetes strikes without warning unless people are in research studies that can detect autoantibodies which reflect inflammation of the pancreas' islet cells that make insulin. Once overt, its costs are high: up to $10,000 a year to treat the disease and up to $50,000 to treat its complications. It's caused by white cells from the blood which attack the pancreas' islets. Some research studies have suggested that there may be a relationship between the timing of the beginning of feeding babies formula, while others failed to show an effect. Recent research in diabetes prone mice and in a preliminary study in babies from Finland, suggest that babies who are fed a special infant formula, if the are not 100% breastfed, are less likely to get the antibodies and therefore possibly diabetes could be delayed or even prevented. Now doctors in the U.S., Canada and in Europe are conducting the TRIGR trial to see if they can prove whether or not the special infant formula helps at-risk babies-those with a parent or sibling who has type 1 or insulin dependent diabetes.

If you are pregnant and your newborn will fit the risk criteria, he or she will be wanted for the trial. The trial does not interfere with breast feeding. Babies who can't breastfeed or need formula in addition to breast milk will get safe infant formulas to see if the test formula helps prevent type 1 diabetes. For details, call 1-888-786-7813 or visit

Dorothy Becker, Professor of Pediatrics
Chief, Division of Endocrinology and Diabetes
Childrens Hospital and University of Pittsburgh

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Last Updated: Sunday January 11, 2004 13:58:24
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