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Alpha Lipoic Acid

Alpha lipoic acid (ALA), also known as thioctic acid, has been used to treat diabetes-related neuropathies. Since it acts as a free radical scavenger and since complications are thought to be secondary to oxidative stress, ALA may help with polyneuropathy symptoms. The ALADIN trials (Alpha lipoic acid in diabetic neuropathy) have demonstrated improvement in different parameters of neuropathy. These trials have shown a decrease in HbA1c although the results were not significant. Long term trials are necessary to determine whether ALA shows progression of neuropathy versus only improvement of neuropathy symptoms. The Neurological Assessment of Thioctic Acid in Neuropathy Study (NATHAN) is an ongoing multicenter trial in Europe and North America to evaluate the ability of oral ALA to slow progression of neuropathy in diabetes.

Go To Gamma Linolenic Acid ...

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Laura Shane-McWhorter, PharmD, BCPS, FASCP, CDE, BC-ADM
November 24, 2001

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			Jump to a new section --[ Getting Around ]-- Home Page What's New Privacy Policy Search --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

Last Updated: Friday August 30, 2002 10:33:14
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