CoQ10 is a vitamin-like substance with a structure similar to Vitamin K. In diabetes it is theorized that using CoQ10 may enhance activity of certain enzymes and may stimulate insulin secretion. It has been studied for a variety of cardiovascular disorders. It may produce GI upset, insomnia, and rare increases in liver enzymes. There are a variety of drug interactions including decreased bleeding time with warfarin use, possible attenuation of the antihypertensive effect of beta blockers and decreased endogenous CoQ10 with statin use. On the other hand, CoQ10 may lessen the toxicity of the chemotherapeutic agent, doxorubicin. In studies involving both type 1 and 2 diabetes, CoQ10 has shown variable effects on diabetes endpoints.
Complementary and Alternative Medicine Pages:
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Laura Shane-McWhorter, PharmD, BCPS, FASCP, CDE, BC-ADM
November 24, 2001
Last Updated: Friday August 30, 2002 10:33:14
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