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Persistent Hyperinsulinaemic Hypoglycaemia of Infancy (PHHI), also known as nesidioblastosis, is a rare, usually inherited condition in which the pancreas produces too much insulin. This is the exact opposite of what happens in type 1 diabetes, but care involves frequent blood sugar tests as with kids with diabetes.

Babies born with PHHI can have severely low blood sugar levels and seizures, and are at high risk for brain damage if blood sugar levels are not maintained at sufficiently high levels. Treatment can include medications, additional feedings, and even removal of up to 90-95% of the pancreas.

Studies

• The outcome in Australian children with hyperinsulinism of infancy: early extensive surgery in severe cases lowers risk of diabetes.

For More Information

• The Congenital Hyperinsulinism Center at The Children's Hospital of Philadelphia is a world-leading center for kids with PHHI
• Sur1 Hyperinsulinism, a web site by parents of kids with nesidioblastosis, is an excellent resource with extensive references
• Nesidioblastosis by Robert S. Gillespie, MD, and Stephen Ponder, MD, CDE
• Ask the Diabetes Team questions about nesidioblastosis

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			Jump to a new section --[ Getting Around ]-- Home Page What's New Privacy Policy Search --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

Last Updated: Tuesday March 09, 2004 15:57:59
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