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Current Research News

1 February 2012

1. Discovery of early-stage biomarkers for diabetic kidney disease using ms-based metabolomics (FinnDiane study). Free full text available in HTML and PDF formats.
2. Spironolactone diminishes urinary albumin excretion in patients with type 1 diabetes and microalbuminuria: a randomized placebo-controlled crossover study.
3. Diabetic retinopathy in the SEARCH for Diabetes in Youth Cohort: a pilot study.
4. Empagliflozin, a novel potent and selective SGLT-2 inhibitor, improves glycaemic control alone and in combination with insulin in streptozotocin-induced diabetic rats, a model of type 1 diabetes mellitus.
5. Serum 25-hydroxyvitamin D level during early pregnancy and type 1 diabetes risk in the offspring.
6. Proinsulin C-peptide interferes with insulin fibril formation.

   25 January 2012

7. Development of a fully automated closed loop artificial pancreas control system with dual pump delivery of insulin and glucagon.
8. Islet autoantibodies and residual beta cell function in type 1 diabetes children followed for 3-6 years.
9. Advanced Glycation End Products as Environmental Risk Factors for the Development of Type 1 Diabetes.
10. A novel strategy for long-term implantable artificial pancreas.

    18 January 2012

11. Safe Glycemic Management during Closed-Loop Treatment of Type 1 Diabetes: The Role of Glucagon, Use of Multiple Sensors, and Compensation for Stress Hyperglycemia.
12. Closed-loop glucose control: psychological and behavioral considerations.
13. Continuous glucose monitoring considerations for the development of a closed-loop artificial pancreas system.
14. A controlled study of the effectiveness of an adaptive closed-loop algorithm to minimize corticosteroid-induced stress hyperglycemia in type 1 diabetes.
15. Meta-analysis of overnight closed-loop randomized studies in children and adults with type 1 diabetes: the cambridge cohort.
16. Neighborhood level risk factors for type 1 diabetes in youth: the SEARCH case-control study.
17. Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
18. Left ventricular filling patterns and its relation to left ventricular untwist in patients with type 1 diabetes and normal ejection fraction.
19. The Timing of Dialysis and Kidney Transplantation in Type 1 Diabetes.

    11 January 2012

20. Reversal of type 1 diabetes via islet beta cell regeneration following immune modulation by cord blood-derived multipotent stem cells. Free full text available in PDF format. See also Novel Stem Cell Treatment May Hold Promise for Type 1 Diabetes and Type 1 Diabetes Reversed With Stem Cells From Cord Blood.
21. Characterization of a Novel Functional Protein in the Pancreatic Islet: Islet Homeostasis Protein Regulation of Glucagon Synthesis in alpha Cells. See also Researchers Discover Protein that May Represent New Target for Treating Type 1 Diabetes.
22. Promoting long-term survival of insulin-producing cell grafts that differentiate from adipose tissue-derived stem cells to cure type 1 diabetes. Free full text available in HTML and PDF formats.
23. 25-Hydroxyvitamin D Concentrations and In Vivo Insulin Sensitivity and beta-Cell Function Relative to Insulin Sensitivity in Black and White Youth.
24. The development and validation of a clinical prediction model to determine the probability of MODY in patients with young-onset diabetes.
25. Blue Flash ERG PhNR Changes Associated with Poor Long-Term Glycemic Control in Adolescents with Type 1 Diabetes.

    4 January 2012

26. Towards an artificial pancreas at home.
27. Advances in pump technology: insulin patch pumps, combined pumps and glucose sensors, and implanted pumps.
28. Regulated and Reversible Induction of Adult Human beta-Cell Replication.
29. Latent Autoimmune Diabetes of Adults Is Phenotypically Similar to Type 1 Diabetes in a Minority Population.

    28 December 2011

30. How does age at onset influence the outcome of autoimmune diseases? Free full text available in HTML and PDF formats.
31. Results of pancreas transplantation alone with special attention to native kidney function and proteinuria in type 1 diabetes patients.
32. Near Normalization of Metabolic and Functional Features of the Central Nervous System in Type 1 Diabetic Patients With End-Stage Renal Disease After Kidney-Pancreas Transplantation.

    21 December 2011

33. Long-Lasting Immune Responses 4 Years after GAD-Alum Treatment in Children with Type 1 Diabetes. Free full text available in HTML and PDF formats.
34. Striated muscle as implantation site for transplanted pancreatic islets. Free full text available in HTML and PDF formats.
35. Glucagon in the Pathogenesis of Hypoglycemia and Hyperglycemia in Diabetes.
36. The D-Lightful Vitamin D for Child Health.

    14 December 2011

37. Increase in the incidence of type 1 diabetes in Israeli children following the Second Lebanon War.
38. Update from the Faustman Lab: Moving Forwrd to Phase 2.

    7 December 2011

39. FDA outlines flexible approaches for artificial pancreas system clinical trials, product approvals See also JDRF Encouraged By Draft FDA Artificial Pancreas Guidance and FDA Issues Artificial Pancreas Guidance Document.
40. Intravital imaging of CTLs killing islet cells in diabetic mice. See also a Jolla Institute researchers provide world's first view of Type 1 diabetes as it unfolds.
41. Type 1 diabetes in Cheshire: Cardiometabolic risk factor trends (2004-2009).
42. End-stage nephropathy in Type 1-diabetes mellitus - Kidney transplantation alone or combined with Islet or pancreas transplantation?
43. Improved Postprandial Glycemic Control in Patients with Type 2 Diabetes from Subcutaneous Injection of Insulin Lispro with Hyaluronidase.
44. Reversal of diabetes by the creation of neo-islet tissues into a subcutaneous site using islet cell sheets.

    30 November 2011

45. Maternal Serum Levels of 25-Hydroxy-Vitamin D During Pregnancy and Risk of Type 1 Diabetes in the Offspring.
46. Impaired diffusing capacity for carbon monoxide in children with type 1 diabetes: is this the first sign of long-term complications?
47. Proinsulin, GLP-1, and glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes.
48. Case report: type 1 diabetes in monozygotic quadruplets.

    23 November 2011

49. An important minority of prediabetic first-degree relatives of type 1 diabetic patients derives from seroconversion to persistent autoantibody positivity after 10 years of age.

    16 November 2011

50. Markedly reduced rate of diabetic ketoacidosis at onset of type 1 diabetes in relatives screened for islet autoantibodies.
51. Closed-loop insulin delivery for treatment of type 1 diabetes. Free full text available in PDF format.
52. Persistent glucose transporter expression on pancreatic beta cells from longstanding type 1 diabetic individuals.
53. Age-corrected Beta cell mass following onset of type 1 diabetes mellitus correlates with plasma C-Peptide in humans. Free full text available in HTML and PDF formats.
54. Diabetes technology and treatments in the paediatric age group.
55. Self-reported lower respiratory tract infections and development of islet autoimmunity in children with the type 1 diabetes high-risk HLA genotype: the MIDIA study.
56. Metabolic function of a suboptimal transplanted islet mass in non-human primates on rapamycin monotherapy.
57. Enteroviruses and type 1 diabetes.
58. Vaccination and risk of type 1 diabetes mellitus in active component U.S. Military, 2002-2008.
59. Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human Evolution. Free full text available in HTML and PDF formats.

    9 November 2011

60. Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes. Free full text available in HTML and PDF formats (link in HTML full text).
61. Current status of immunomodulatory and cellular therapies in preclinical and clinical islet transplantation. Free full text available in HTML and PDF formats.
62. Otelixizumab in the treatment of Type 1 diabetes mellitus.
63. Association of Epilepsy and Type 1 Diabetes Mellitus in Children and Adolescents: Is There an Increased Risk for Diabetic Ketoacidosis?
64. High levels of immunoglobulin E and a continuous increase in immunoglobulin G and immunoglobulin M by age in children with newly diagnosed type 1 diabetes.
65. Identification of Small Molecule Inhibitors that Suppress Cytokine-Induced Apoptosis in Human Pancreatic Islet Cells. Free full text available in HTML and PDF formats.

    2 November 2011

66. Age- and islet autoimmunity-associated differences in amino Acid and lipid metabolites in children at risk for type 1 diabetes.
67. Helicobacter pylori infection might be responsible for the interconnection between type 1 diabetes and autoimmune thyroiditis.
68. Metabolic Control and Bone Health in Adolescents with Type 1 Diabetes.

    19 October 2011

69. Real-Time Adaptive Models for the Personalized Prediction of Glycemic Profile in Type 1 Diabetes Patients.

    12 October 2011

70. U-100, pH-Neutral Formulation of VIAject(®) : Faster Onset of Action than Insulin Lispro in Patients with Type 1 Diabetes.
71. Exposure to the Viral By-Product dsRNA or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis via a Bim / Mcl-1 Imbalance. Free full text available in HTML and PDF formats.
72. Circulating Endothelial Progenitor Cells and Large Artery Structure And Function In Young Subjects With Uncomplicated Type 1 Diabetes. Free full text available in PDF format.
73. Sensitization to Gliadin Induces Moderate Enteropathy and Insulitis in Nonobese Diabetic-DQ8 Mice.
74. Neonatal jaundice is associated with a small increase in the risk of childhood type 1 diabetes: a meta-analysis of observational studies.

    5 October 2011

75. Automatic Learning Algorithm for the MD-Logic Artificial Pancreas System.
76. Reduced Prevalence of Diabetes Ketoacidosis at Diagnosis of Type 1 Diabetes in Young Children Participating in Longitudinal Follow-Up.
77. Reclassification of diabetes type in pediatric patients initially classified as type 2 diabetes mellitus: 15 years follow-up using routine data from the German/Austrian DPV database.

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Last Updated: Wednesday February 01, 2012 16:36:33
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