Use of Lispro Insulin Instead of Regular in an Insulin Pump Improves ControlIn Improvement of HbA1c and Blood Glucose Stability in IDDM Patients Treated With Lispro Insulin Analog in External Pumps, by V. Melki, MD, et al, Diabetes Care 21:977-82, 1998, researchers report that the use of Lispro Insulin instead of Regular in an insulin pump improves both HbA1c and overall blood glucose values, while at the same time reducing the number of serious low blood sugars.
In the study, patients used Lispro Insulin or Actrapid (Regular) for three months, then switched to the other insulin. 38 patients who completed the study. A1c levels dropped from 7.74 (+/- 0.20) to 7.11 (+/1 0.15%) with Lispro and from 7.97 (+/- 0.13) to 7.88 (+/- 0.16%) with Actrapid. Mean daily blood sugars were also lower when using Lispro compared with Actrapid (7.93 +/- 0.15 mmol/l [142.7 mg/dl] vs. 8.61 +/- 0.18 [154.9 mg/dl]).
At the end of the study, patients were asked which insulin they wanted to continue using. 36 of 38 (95%) chose Lispro.
Posted 24 May 1998
Last Updated: Thursday February 27, 2014 19:28:21
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
© Children with Diabetes, Inc. 1995-2016. Comments and Feedback.