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Question: From Toronto, Ontario, Canada: I have read the statistics you have provided in response to other questions regarding the hereditary nature of diabetes. I understand that the chance of a child becoming diabetic if the father is Type 1 is between 3 and 10%. What would be the difference in the percentages related to the following two issues: The length of time the father has been diabetic? (In this case, he is 22 and has had Type 1 for 13 years.) A history of Type 1 late-onset diabetes in the mother's family? (Both her grandmother and great uncle developed late-onset Type 1 diabetes.) Would these factors significantly increase the chances of a child becoming diabetic, or does the percentile remain relatively the same? Answer: This question was referred to several pediatric endocrinologists, who have each given an answer: Answer from Dr. Robertson: Not strictly an answer to the question but the following may be pertinent. The offspring of a diabetic father have a slightly higher risk than those of a diabetic mother. I am not aware of any influence of the age of the parents or other relatives or of their duration of diabetes. However, there is a marked reduction in the risk of developing IDDM above the age of 40 even in those who are found to be ICA positive. The lifetime risk for siblings of a diabetic is 6.6 +/- 1.1%, for children 4.8 +/- 1.7%. KJR Answer from Dr. Stuart Brink: The duration of IDDM in father is only important in that there are many years of discordance - but I do not know actual statistics to answer the question posed. I think the best stats that I have seen suggest father to child inheritance of IDDM around 5-6% compared to mother to child around 2-3%. The older relatives are so far removed that I do not think that they play a great part statistically except to increase the percentages just a tad. SB Original posting 4 Jan 97

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			Jump to a new section --[ Getting Around ]-- Home Page What's New Privacy Policy Search --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

Last Updated: Tuesday April 06, 2010 15:08:51
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