From Arkansas, USA:
My son who is 28 and has had Type 1 Diabetes for 3 years heard something on a TV local news show about nasal spray insulin, but we have not been able to find out anything about it. Has there been any recent developments in the research or testing of nasal spray of Insulin? It is our understanding that previous results have not been very reliable.
The idea of trying to control diabetes with insulin by nasal spray has long been a beguiling one. A few years ago it was tried again as a way of managing mild degrees of acidosis. It is unsatisfactory however firstly because it requires a much more concentrated insulin and secondly because absorption is erratic. The same criticisms can be made about iontophoresis another 'injection avoiding' process.
Studies are now underway and being planned for using insulin as a means of 'vaccinating' or 'tolerising' susceptible persons against diabetes. In this situation absorption is much less critical and both oral and intranasal routes are being considered.
Original posting 14 Feb 97
Last Updated: Tuesday April 06, 2010 15:08:52
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