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From Seattle, Washington, USA:

Is there a role for chromium dietary supplementation in the control of insulin needs for either IDDM or NIDDM? Any difference between "GTF" chromium and chromium picolinate?


Chromium is not thought to be of any help in Type 1 Diabetes (IDDM). There have been a number of studies claiming some benefit in a variety of cause of impaired glucose tolerance including malnutrition and NIDDM. The proposed mechanism is an enhancement of receptor sensitivity.

Glucose Tolerance Factor or GTF is derived from brewer's yeast and some enhancement of insulin action has been claimed. Supposedly it is a complex of trivalent chromium and nicotinic acid; but other studies have cast doubts on GTF as an entity. Chromium picolinate is a common dietary supplement which has attracted some attention for its alleged potential to increase body mass in both man and animals. Claims have also been made for improved glucose tolerance and help in depressive states.

If you have access to a medical li depressive states.

If you have access to a medical library you might read the Journal of Nutrition 124:117, 1994. The field has recently lacked enthusiasm at least in part because of the considerable difficulty of measuring trace amounts of chromium accurately.


Original posting 19 Mar 97


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Last Updated: Tuesday April 06, 2010 15:08:54
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