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Question:

From Philadelphia, Pennsylvania, USA:

What is amylin? I read that a biotech company was recently granted a patent on a synthetic form of this hormone, which they claim holds great promise in the treatment of Type 1 diabetes.

Answer:

Amylin is a hormone which is secreted by the beta cells in the pancreas along with insulin. Therefore it is (like insulin) deficient in Type 1 diabetes mellitus.

It seems to inhibit gastric emptying (so reducing glucose absorption by the gut) and by inhibiting glucagon secretion (another hormone that has glucose raising effects).

Studies are underway using a synthetic analogue of amylin (pramlintide) and in preliminary work it seems to help control blood sugars.

KJR

[Editor's comment: The manufacturer of pramlintide has a website, at http://www.amylin.com/. WWQ]

Original posting 22 Feb 1998
Posted to Research: Other

  
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Last Updated: Tuesday April 06, 2010 15:08:56
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