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Question:

From Michigan, USA:

I have a 6 year old with Fragile X syndrome who was diagnosed with Type 1 approximately one year ago. In the last 10 months, he has been in the hospital twice with seizures due to lows and once with dehydration due to the flu. Every time has been in the ICU. Is this common and is he likely to have many more hospitalizations? Is he more at risk than other children?

Answer:

There is no specific association, either chromosomal or biochemical, between the Fragile X Syndrome. and Type 1 autoimmune diabetes. However he is likely to have a diminished ability to express how he feels and this will make him more vulnerable to hypoglycemic episodes.

The way to prevent this is to make sure that you do enough blood sugars to have a good idea as to what his normal pattern is and then to have supplementary measurements in relation to exercise and vagaries of appetite. If you are not already doing so you might think to discuss with his doctor the use of lispro insulin [Humalog® brand] rather than Regular insulin. Because this insulin takes effect more quickly, it can be given after the meal and the dose can thus be adjusted both to the pre-meal blood sugar and to his appetite. Finally in trying to establish usual patterns of blood sugar levels, you should occasionally include levels at around 2 A.M. Also, if you know that he is likely to have a fall in blood sugar at some time after vigorous exercise you will need to supplement his carbohydrate intake appropriately to prevent this.

DO'B

Original posting 26 Mar 1998
Posted to Other Illnesses

  
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Last Updated: Tuesday April 06, 2010 15:08:58
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