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From Spokane, Washington, USA:

How does a glucose analyzer operate and what chemical reactions are carried out on the strip?


Development in the field of home blood glucose monitoring has been explosive since the introduction in 1978 of two types of glucose oxidase strips, both designed to be read visually or with a meter, Dextrostix (Ames) and Reflotest/Chemstrip (Boehringer Mannheim).

Different colors of the chemical reagent pad of the strip are based on the enzymatic glucose oxidase method. The enzyme glucose oxidase oxidizes glucose to gluconic acid and H2O2 (hydrogen peroxide) which in turn - and in accordance with the glucose concentration in the drop of blood applied on it - makes the color of the pad change. This color change can be read visually or through a reflectance meter.

Some of the newer generation sticks, e.g., Elite and Medisense, which can only be read by a meter, are based on the tiny electrical impulses generated in the process of glucose oxidation by the same glucose oxidation.


Original posting 17 Jun 1998
Posted to Blood Tests and Insulin Injections


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Last Updated: Tuesday April 06, 2010 15:08:58
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