advertisement
 

  Back to Ask the Diabetes Team Ask the Diabetes Team
Question:

From Santa Clarita, California, USA:

Is there a difference between NPH and Lente insulin? I heard that Lente lasts just a little bit longer than NPH. (Note: I am not talking about Ultralente.)

Answer:

NPH and Lente are both "intermediate" acting insulins. Their time of action is very similar, though in some individuals Lente lasts slightly longer. The main difference in the two insulins is that different chemicals are added to Regular insulin to delay its onset of action and make it last longer.

NPH was developed first. Lente was developed with the hope that it would cause fewer problems with allergic reactions. In reality, most of the allergic reactions in the past were due to the impurities in the insulin which was extracted from beef and pork pancreases. Now that insulin is made synthetically, is identical to human insulin, and contains no animal impurities, allergy to either NPH or Lente is extremely rare. (This is also true for the pork insulins still on the market as extra purification steps are now included in the manufacturing process to remove the animal impurities.)

TGL

Original posting 18 Aug 1998
Posted to Insulin

  
advertisement


                 
  Home Return to Top

Last Updated: Tuesday April 06, 2010 15:08:58
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2015. Comments and Feedback.