Advertisement

		Ask the Diabetes Team	Jump to a new section --[ Getting Around ]-- Home Page What's New Guide to CWD Help with Error Messages Index Privacy Policy Search Site Map --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Get CWD Products Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

Question: From New York, New York, USA: I was diagnosed with Type 2 at 51. I spent six months on oral agents, then switched to insulin. Two years later I developed hypothyroid, and am now on thyroid replacement hormone. My diabetes diagnosis was changed to type 1. I also have pancreatitis; but not the kind associated with diabetes. I'm now 56. My insulin needs vary, 16 to 27 units in a 24 hour period. I weigh 165 lbs. I probably should need 40 or more units. Daily monitoring is good and A1C shows good. In your answers to some other questions I noticed a reference to slowly developing type 1. I would like to know more about this from you and perhaps you can provide some reading suggestions also. I also noticed you have reference to insulin antibodies as a cause of type 1. I would like to know more about this and whether or not it may be a factor. knockatee@AOL.com">Type 1? Answer: I am not surprised that your doctor changed the original diagnosis of Type 2 Diabetes to Type 1 after you developed hypothyroidism. Nowadays this combination might be referred to as one of the autoimmune polyglandular syndromes (Type II). To prove this it would be necessary to do a spectrum of antibody tests; but the results would not really affect treatment even though you seem to be on a very low dose of insulin. The pancreatitis is not reported as an associated autoimmune condition although of course, there are a number of situations in which diabetes may in fact be secondary to a chronic pancreatitis. Fitting the pancreatitis with the hypothyroidism and the diabetes all into one syndrome does not seem to be possible. And there are some other very rare possibilities; but the difficulties and expense of a specific diagnosis are so far not cost-effective in leading to better treatment. Autoimmune diabetes has been reported as late as the sixth decade. Anti-insulin antibodies do not seem to have a role in promoting Type 1 diabetes; but the B9-23 peptide of insulin may have a role in helping to trigger lymphocyte activation by an antigen presenting cell with a specific genetic pattern. Without knowing a little bit more of your capacity for technical jargon, I hesitate to suggest a reading list; but you might venture into PubMed using 'autoimmune polyglandular syndrome' as the research phrase. Another way if you live near a medical library would be to have one of the librarians steer you through a program like OVID which also accesses the national Library of Medicine. DO'B Original posting 7 Sep 1998 Posted to Diagnosis and Symptoms

Advertisement

Not Helpful  1 2 3 4 5  Very Helpful                  E-mail Page     Print Format
			Jump to a new section --[ Getting Around ]-- Home Page What's New Guide to CWD Help with Error Messages Index Privacy Policy Search Site Map --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Get CWD Products Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

Last Updated: Sun Jan 15 12:03:04 2006
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by Children With Diabetes, Inc, which is responsible for its contents.
By using this site, you agree to our Terms of Use, Legal Notice and Privacy Policy.
© Children with Diabetes, Inc. 1995-2008. Comments and Feedback.