What are anti-gad antibodies?
GAD stands for glutamic acid decarboxylase which is an enzyme common to all cells. When immunological damage to the insulin-producing islet cells begins, there is a release of this and other enzymes and antibodies are formed (anti-GAD). Anti-GAD together with anti-insulin antibodies and another antibody called ICA512 are used either to detect preclinical damage to the islet cells in Type 1A diabetes or to confirm that that is indeed the correct diagnosis. Many laboratories in doing this routine testing also look for anti-transglutaminase and anti-21-hydoxylase, markers of two other autoimmune conditions that are significantly, but not commonly, linked to Type 1A Diabetes.
Original posting 13 Sep 1998
Posted to Research: Causes and Prevention
Last Updated: Tuesday April 06, 2010 15:09:00
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
© Children with Diabetes, Inc. 1995-2016. Comments and Feedback.