Back to Ask the Diabetes Team Ask the Diabetes Team

From America On-Line:

My father has type 2 diabetes and Hepatitis C. He is currently taking Glucophage (metformin), and has tried Glucotrol (glipizide, a sulfonylurea). I recently read that both of these can be harmful to the liver of people that have liver disease. Are there any prescription drugs for type 2 diabetes that aren't harmful to the liver?


Fortunately, it is rare that either of these two drugs harm the liver. (On the other hand, a different medication, troglitazone, can cause reversible damage in about 2% of people taking it, and is not advised for people with any liver disease.)

All diabetes drugs have side effects, which is why they are prescription medications in the first place! Your dad should discuss their possible side effects with his physician. If his doctor isn't sure, the doctor can contact the manufacturer or his friendly local endocrinologist for additional advice on which to choose.

I can recall a case or two where my patient with liver disease, and I decided to use insulin (which doesn't adversely affect the liver) instead of pills, because the patient had liver disease and the pills weren't appropriate.


Original posting 24 Sep 1998
Posted to Medications: Pills for Diabetes


  Home Return to Top

Last Updated: Tuesday April 06, 2010 15:09:00
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2015. Comments and Feedback.