From Alberta, Canada:
Can glucosamine sulfate increase blood glucose in people with diabetes? From what I've read so far, it seems as glucosamine might not break down to glucose, but it may impair glucose-induced insulin release (animal studies). Have you heard of any human studies? Should people with diabetes avoid it?
In the last few years glucosamine sulfate has become accepted as an alternative to nonsteroidal anti-inflammatory drugs like ibuprofen in the treatment of osteoarthritis. It is reputed not only to diminish pain, but also to have some restorative action on the joint surfaces. There have not been any well organised clinical trials, however.
The normal dose of glucosamine is insufficient to affect blood sugar even in a diabetic and in any case it is rapidly attached to serum proteins or to cartilage tissues.
On the other side, there is some rather tenuous evidence that glucosamine can induce a degree of insulin resistance and is involved in some way in the development of diabetic nephropathy (kidney disease). On balance I think that a person with Type 2 diabetes and osteoarthritis should avoid glucosamine unless the uncertain disadvantages are offset by a conspicuous benefit to the arthritis. This is an issue to be discussed with the physician involved.
Original posting 3 Oct 1998
Posted to Other Medications
Last Updated: Tuesday April 06, 2010 15:09:00
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
© Children with Diabetes, Inc. 1995-2015. Comments and Feedback.