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Question:

From Bogota, Columbia:

Does Thalassemia have anything to do with diabetes?

Answer:

In thalassemia (also called Cooley's disease), there is a genetic defect in the synthesis of some alpha or beta chains of hemoglobin, an iron-protein of the red cells which carries oxygen to tissues, with consequent anemia. This leads towards excessive storage of iron, as a result of both chronic hemolysis and repeated blood transfusions, especially in the liver and other tissues, including the pancreas and the skin. Pancreatic involvement may sometimes lead to destruction of islet cells and to a secondary form of insulin-requiring diabetes.

MS

Original posting 8 Jan 1999
Posted to Other Illnesses

  
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Last Updated: Tuesday April 06, 2010 15:09:02
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