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From California, USA:

Can you give an explanation of what a condition called Gad 65 is? I'm a 13 year old male.


If it is in relation to diabetes, the abbreviation GAD refers to an intracellular enzyme called 'glutamic acid decarboxylase'. When the beta or insulin producing cells in the islets are damaged this enzyme is liberated into the blood stream and the body forms specific antibodies to it which are often described as GAD65 or anti-GAD65. This antibody is part of a spectrum of antibodies used in the diagnosis of Type 1A or autoimmune diabetes. These antibodies can be present long before there is an actual need for insulin.


Original posting 1 May 1999
Posted to Diagnosis and Symptoms


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Last Updated: Tuesday April 06, 2010 15:09:02
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