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Question: From a physician in Massachusetts, USA: My 4 year old grandson has type 1 diabetes. Please advise which of these insulins may be mixed together in the same syringe for his injection, without adversely affecting each other: Humalog, NPH, Ultralente, Regular. Answer: Officially approved by Eli Lilly: You can mix Humalog with NPH or Ultralente in the same syringe. You can mix Regular with NPH or Ultralente in the same syringe Not "officially approved" but published in studies: Mixing Regular and Humalog together in the same syringe Officially not recommended Mixing NPH with Ultralente in the same syringe. According to Eli Lilly the phosphate in the NPH theoretically could precipitate the zinc in the Ultralente. From what I have been told, this is a theoretical concern that has never actually been reported, Humalog by the way also has phosphate and has been extensively studied and approved to mix in the same syringe with Ultralente. I have never been able to get a clear explanation from Eli Lilly why mixing NPH and Ultralente should be a problem but not mixing Humalog and Ultralente. Here is the mixing guidelines in chart form: Insulin Mixing Guide Insulin Humalog Regular NPH Lente UltraLente Humalog   Yes* Yes Yes Yes Regular Yes*   Yes Yes Yes NPH Yes Yes   No No Lente Yes Yes No   Yes UltraLente Yes Yes No Yes   * Not officially approved but published in studies. I personally have many patients mixing Regular, Humalog, Lente, and Ultralente in the same syringe with no problem. I am aware of many physicians who have their patients mix NPH and Ultralente (with Regular or Humalog ) in the same syringe with no problem. I suggest that patients or parents ask their own doctor what he or she recommends. TGL DTQ-19990507230540 Original posting 29 Jun 1999 Posted to Insulin

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			Jump to a new section --[ Getting Around ]-- Home Page What's New Privacy Policy Search --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

Last Updated: Tuesday April 06, 2010 15:09:04
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