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Question: From Bethesda, Maryland, USA:
I have heard that hypoglycemia in children and young adults is now considered a possible pre-diabetic condition. What metabolic changes lead from hypoglycemia to hyperglycemia with aging?
Answer:
The hypoglycemia that is an occasional predictor of clinical diabetes is due to a delay in what is called 'first phase insulin release'. What this means is that the normal prompt response of the islet cells to a rise in blood sugar is not yet absent; but is delayed for several hours. This in turn leads to inappropriate hyperinsulinemia at a time after a meal when the glucose rise has subsided.
DTQ-19990426100817
Original posting 1 Jul 1999
Posted to Hypoglycemia and Diagnosis and Symptoms
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Last Updated: Sun Jan 15 12:06:34 2006
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