Back to Ask the Diabetes Team Ask the Diabetes Team

From Amherst, Ohio, USA:

My 3 year old son was diagnosed as Insulin dependent 5 months ago after contracting E. coli which resulted in Hemolytic Uremic Syndrome. The doctors are not sure what has caused him to be insulin dependent except to say that the HUS somehow affected his pancreas causing severe pancreatitis. Our pediatricians and endocrine doctors have all told us that in their research they have not seen a case of HUS which caused insulin dependence but they have no reason to believe he is a type 1 diabetic.

Have you ever heard of insulin dependence resulting from HUS or E. coli and if so, what is the possibility this is not a permanent condition like type 1 diabetes?


Although I have not personally seen an association of insulin dependent diabetes and hemolytic uremic syndrome, this apparently has been reported. You may want to search PubMed under hemolytic uremic syndrome and diabetes.

Testing for antibody against islet cells, insulin, and GAD may help tell whether the stress of the illness brought out latent, developing autoimmune diabetes, or whether the diabetes was secondary to damage to the pancreas caused by the illness. In either case, the treatment is probably the same.


Original posting 2 Jul 1999
Posted to Research: Causes and Prevention


  Home Return to Top

Last Updated: Tuesday April 06, 2010 15:09:06
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2015. Comments and Feedback.