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Question:

From Alameda, California, USA:

My sister "inherited" type 1 diabetes at age 7. My mom says it is a genetic disorder, and if it is, from what gene does it come?

Answer:

Assuming that your sister has the commonest form of diabetes in childhood in the US, that is, Type 1A which is due to a disorder of the immune system then the main genetic locus is on Major Histocompatibility Complex (MHC) locus of Chromosome 6. There are a number of other genes also involved. If you would like to read about this in a great deal more detail try http://www.uchsc.edu/misc/diabetes/oxch7.html.

DOB

DTQ-19990204150838
Original posting 24 Jul 1999
Posted to Genetics and Heredity

  
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Last Updated: Tuesday April 06, 2010 15:09:06
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