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Question: From Carlisle, Pennsylvania, USA: I was just wondering if they have found out which gene is responsible for diabetes. If they have, I would really appreciate knowing which one or if you could lead me in the right direction to find it. Answer: Different forms of diabetes mellitus show different genetic patterns. In Type 1A or autoimmune diabetes, which is the commonest form in Caucasian children in North America, there is a genetically determined susceptibility to the disorder which has to be triggered by a so far unknown environmental component before insulin dependent clinical diabetes can develop. The several alleles that determine this predisposition are located in the Main Histocompatability Complex (MHC) region on the short arm of chromosome 6. Other loci on chromosomes 2, 11, 15 and 18 may also play a role. A more detailed description of all of this together with many references can be found in Chapter 7 of George Eisenbarth and Kevin Lafferty's book on Type 1 diabetes which you can find at www.uchsc.edu/misc/diabetes/oxch7.html. The text is somewhat technical though, so be prepared. DOB DTQ-20000329141034 Original posting 20 Jun 2000 Posted to Genetics and Heredity

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			Jump to a new section --[ Getting Around ]-- Home Page What's New Privacy Policy Search CWD --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

Last Updated: Sun Jan 15 12:06:41 2006
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