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Question: Is Moduretic (a thiazide) or Atenolol (a beta blocker) contraindicated in Type 2 diabetes? I thought both of these would make blood sugars rise. Answer: You are correct in supposing that both the thiazide drugs and the beta blockers without intrinsic sympathomimetic activity increase glucose intolerance in Type 2 diabetes. This is especially so when they are used together; but the problem can be circumvented by using ACE inhibitors as a first antihypertensive drug and by reducing the thiazide dose to as little as 6.25 mg hydrochlorothiazide a day. The mechanisms are complex, but you can find several reports by searching in PubMed. DOB DTQ-20000423203220 Original posting 1 Jul 2000 Posted to Other Medications

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			Jump to a new section --[ Getting Around ]-- Home Page What's New Privacy Policy Search --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

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