From Georgia, USA:
Can a family member be a donor for pancreas cells? How old should you be to be eligible for this?
At the present time, all pancreas islet transplants have to be based on cadaver organs. No one has yet been able to culture human islets, so the problem of availability of donors is a real one. Theoretically, it would be possible to remove a pancreas from a family member and transplant it, but the immediate risk to the donor of the surgery and the exigencies of replacement therapy for both insulin and digestive enzymes does not justify this.
For the time being, transplant of whole pancreas has become a remarkably successful procedure which is mostly used for subjects who also need a kidney transplant. A group in Canada have just reported a remarkably successful procedure for islet cell transplants though it takes the islets of two pancreas's to have sufficient donor material. There is a group in New Zealand that are preparing to try a technic for using porcine islet cells that have been encapsulated to protect them against autoimmune damage. For all these successes, conventional therapy with new insulins and new dosage scheduling together with minimally invasive blood glucose sampling has much to recommend it as the treatment of choice.
[Editor's comment: See Alberta Foundation Reports on Successful Islet Transplants for more information. WWQ]
Original posting 11 Sep 2000
Posted to Research: Cure
Last Updated: Tuesday April 06, 2010 15:09:14
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
© Children with Diabetes, Inc. 1995-2017. Comments and Feedback.