From Hartsdale, New York, USA:
Have there been many cases of children diagnosed with type 1 recently who are later re-diagnosed? My 14 tear old son was diagnosed 15 months ago with type 1 diabetes by a doctor who told us there was no chance that his diabetes was reversible or temporary. This week, after new lab tests and following a month of very low blood sugars and no insulin, a different doctor told us that our son is producing insulin. Have you seen similar cases? If so, has the diabetes recurred later on? Does anyone know what can trigger this type of diabetes?
The great majority of new onset cases of diabetes in children in North America that require insulin are due to a disorder of the immune system that slowly destroys all the insulin producing cells. This is called typeá1A or autoimmune diabetes and requires insulin for life. About 5% of the subjects who present like this in Caucasian families, but just over 50% of those from African American or Hispanic families have a different form of diabetes called typeá1B. The two groups can be differentiated at the outset by an antibody test which is positive in type 1A and negative in type 1B. This is quite an expensive test so that doctors tend to wait and see because the initial treatment of the two groups is exactly the same. In type 1B, however, the type which I think your son must have, about 50% can manage without insulin after a variable number of weeks or months. They may continue to need oral hypoglycemic agents to keep in good control, but others may manage with just diet and lots of exercise. The underlying pathology of this second group is not yet well understood, although some are known to show chromosomal changes. There is very little data to judge the long term prognosis. What there is, however, suggests that there is an underlying insulin deficiency and that at some time in the future it may again need to be given.
Original posting 15 Nov 2000
Posted to Diagnosis and Symptoms
|Return to the Top of This Page|
Last Updated: Tuesday April 06, 2010 15:09:16
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
© Children with Diabetes, Inc. 1995-2018. Comments and Feedback.