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Question: From Winona, Minnesota, USA: In a previous answer, you told a patient, " your pancreas is unlikely to come back if it is completely removed, but almost complete regeneration, within a year, has been reported after partial resection for a benign tumor." If the pancreas is able to regenerate itself, why can't it resume production of insulin or be stimulated to produce insulin in type 1 diabetes? Answer: The reason that insulin producing cells in the pancreas cannot regenerate is because the basic autoimmune disorder (which is not present after surgically induced diabetes) in type 1A (autoimmune) diabetes still persists. At the present moment the best prospect seems to be to replace islet cells surgically under the cover of some of the new immunosuppressive agents like tacrolimus and serolimus. Other groups are trying to do this with porcine islets that are specially encapsulated to resist immune destruction and, one day, perhaps it will be possible to induce new islet tissue using stem cells, but continued immunosuppression, of some sort, including chimera induction will still be needed. DOB DTQ-ONCEM200010241146 Original posting 26 Nov 2000 Posted to Research: Cure

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			Jump to a new section --[ Getting Around ]-- Home Page What's New Privacy Policy Search --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

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