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Question: From Virginia, USA: I have several questions which I hope you might answer: In type 1 diabetes, the pancreas cells are destroyed due to various viruses, GAD, etc. Is the difference between type 1A and type1B is that one is due to a virus, and one is not? Can a type 1A state be permanent, but have no antibodies in the blood? (not due to trauma) Could the antibodies that caused type 1A diabetes spontaneously disappear? Could regenerated cells (from the same person) be re-transplanted into a type 1 with no antibodies with no further damage to the cells? Answer: The difference between type 1A and type 1B diabetes is that, in the former, there are one or more specific antibodies in the blood at the time of diagnosis. Yes, antibodies may disappear after the insulin producing cells have been destroyed. Assuming that insulin producing cells from early in the course of type 1A diabetes could be biopsied and cultured (not possible at this time), they would be destroyed on reintroduction by the continuing autoimmune process which is vested in certain lymphocytes not in the presence of antibodies. This approach has been tried with the partial transplantation of the pancreas between identical twins, and it did not succeed for the above reason. DOB DTQ-20001126174736 Original posting 14 Dec 2000 Posted to Research: Causes and Prevention and Research: Cure

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			Jump to a new section --[ Getting Around ]-- Home Page What's New Guide to CWD Help with Error Messages Index Privacy Policy Search Site Map --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Get CWD Products Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

Last Updated: Sun Jan 15 12:18:23 2006
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