From the Bronx, New York, USA:
My husband and two children all have type 1 diabetes. If we decided to have more children, Is there any test to predict if that child would develop diabetes?
At the present there is no such test. The overall chance of a third child having type 1A (autoimmune) diabetes is still about 1:20 in Caucasian families, and it may be just statistical happenstance that your husband and two children are already affected. At the same time, one can't help wondering if the population average has not been biased in your case by some genetic factor or especial exposure to one of the as yet unknown environmental triggers of actual clinical diabetes. In a few years, it might be possible to make a much more accurate prediction on the basis of amniocentesis of fetal cells, but at present, the only way to refine the general figure would be for you and your husband both to be HLA (Human Leukocyte Antigen) typed to find out whether you both were homozygous for high risk genes, had a protective gene or were somewhere in between.
Original posting 10 Mar 2001
Posted to Research: Causes and Prevention
Last Updated: Tuesday April 06, 2010 15:09:20
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
© Children with Diabetes, Inc. 1995-2015. Comments and Feedback.