advertisement
 

  Back to Ask the Diabetes Team Ask the Diabetes Team
Question:

From Hooksett, New Hampshire, USA:

My two year, nine month, son was diagnosed with type 1 diabetes eight months ago, and recently was screened for celiac disease, even though he has no symptoms. His antibody test results are as follows: anti-gliadian - 71 (normal less than 20) and IgA - 7 (normal less than 20). We will be seeing a pediatric gastroenterologist, but there is a long wait. Since one of the antibodies is negative, is this still a positive test for celiac disease? I'm confused by the conflicting test results.

Answer:

The antigliadin test is not very specific and is less and less used for the diagnosis of celiac disease. In the absence of symptoms, I would ignore it. However, you do need to ask your son's diabetes doctor exactly what the IgA test represented. I assume that this was either for anti-endomyseal antibodies or anti-transglutaminase antibodies, both of which are IgA's. Depending on the laboratory, the level of anti-transglutaminase antibodies can be used to predict damage to jejunal mucosa, and thus, in large measure, dispense with the need for a biopsy before deciding the need for a gluten free (wheat free) diet. I suspect though that either your diabetes team or the gastroenterologist will want to repeat the anti-transglutaminase test at intervals just as they probably will test for hypothyroidism.

DOB

DTQ-20010305170830
Original posting 18 Mar 2001
Posted to Other Illnesses

  
advertisement


                 
  Home Return to Top

Last Updated: Tuesday April 06, 2010 15:09:20
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2015. Comments and Feedback.