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Question:

From Dallas, Texas, USA:

Fifteen months ago, my 12 year old son was diagnosed with typeá1 diabetes. He weighs 40 kilograms, his current total daily insulin requirement is 20 units, and his last hemoglobin A1c was 8.2%. I was told that an average total insulin need for a person like my son is 1.5 Units per kilogram of body weight per day. That would mean he should be taking 60 Units. Is 1.5 units per Kilogram correct? If so, are his beta cells producing more that 50% of his body's needs?

Answer:

I think that most children's diabetes doctors would consider a total daily dose of insulin of 1.5 Units per kilogram of body weight per day to be quite high. A more usual figure would be between 0.8 and 1.0 Unit per kilogram of body weight per day, and your son is getting 0.5 Unit per kilogram of body weight per day. So you are correct in supposing that he is still making a significant proportion of his insulin needs.

To be doing so well 15 months from the onset is a little unusual, so you might think to talk to his doctor and see if it would be possible to get a serum C-peptide test which would confirm this. It might also be worth asking whether he had an antibody test at first diagnosis which would have confirmed that he has typeá1A (autoimmune) in which insulin production is ultimately completely destroyed and not typeá1B which has a similar acute onset, but in which, in about 50% of cases, insulin is gradually no longer required for a period of time.

DOB

DTQ-20010423140115
Original posting 29 Apr 2001
Posted to Daily Care

  
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Last Updated: Tuesday April 06, 2010 15:09:22
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