Back to Ask the Diabetes Team Ask the Diabetes Team

From Atlanta, Georgia, USA:

I have type 1 diabetes and am planning on conceiving my second child. When I had my first child, I was taking NPH with Regular and had no problems, but now I am taking NPH with Humalog and my doctor wants to try Lantus instead of NPH. I'm a little worried about being on different medication from the first pregnancy. Are Humalog and Lantus safe for the unborn baby and for nursing?


Neither one of these types of insulin have been formerly investigated in pregnancy. I have used Humalog in pregnancy with good results and no bad outcomes which is probably the general experience. There was a letter published in The New England Journal of Medicine that expressed concern about Humalog, because of a possible increased risk of fetal abnormalities. However, this was not a scientific study, and I have heard nothing further.

I have not used Lantus (insulin glargine) and have had not patients yet who came to me already on this type of insulin. If you want to minimize your risks, I would suggest using R and N during the first 10 weeks of pregnancy and then switching over to the other types. There should be no problems with breast feeding.


Original posting 25 Jul 2001
Posted to Family Planning


  Home Return to Top

Last Updated: Tuesday April 06, 2010 15:09:24
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2015. Comments and Feedback.