From London, United Kingdom:
I am 15 years old and as an infant, I had a sub-total pancreatectomy because of nesidioblastosis which has left me with type 1 diabetes. Are there any tests I need to go through before I can have children? If I had children in the future would they be at a higher risk of developing nesidioblastosis?
The recommendations to you would be the same as for anyone else with type 1 diabetes. Essentially, you should be in good glucose control prior to conception and maintain that throughout the pregnancy. You should also be taking extra folic acid (1 mg/day) to reduce the risk of neural tube defects.
Nesidioblastosis is an autosomal recessive disorder. This means that if you have a child with someone who carries the gene, but is not affected, then the risk of a child with nesidioblastosis is 50% and of being a carrier (no disease) is also 50%. However, if you have a child with someone who does not carry the defect, then your child would only be a carrier. Nesidioblastosis is rare (I do not know the incidence in the population), thus the chances of having a child with someone who is a carrier is low. I would strongly suggest that you meet with a genetic counselor before you decide to have children to discuss this further.
Original posting 22 Nov 2001
Posted to Family Planning
Last Updated: Tuesday April 06, 2010 15:09:28
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
© Children with Diabetes, Inc. 1995-2015. Comments and Feedback.