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Question:

From Burlington, Ontario, Canada: I have diabetes and recently, during a physical exam for insurance, I had a blood creatinine of 0.9 mg/dl (normal range: 0.5 to 1.5 mg/dl) and urine creatinine of 16.9 mg/dl (normal range: 27.0 to 260.0 mg/dl) along with a urine microalbumin of 0.7 mg/dl (normal range: 0.0 to 3.0 mg/dl)). These figures work out to a microalbumin/creatinine ratio of 41.42 (normal range: 0.0 to 30.0) which the insurance company says this is not good and is an early sign of liver or kidney problems. have searched all over the Internet for what low urine creatinine means, and I can't find anything that explains what the danger is. Can you help?

Answer:

The point here is not a low creatinine concentration, but an elevated microalbumin/creatinine ratio. This implies early diabetes involvement of the kidney. In patients with type 2 diabetes, it is also associated with cardiovascular disease.

You need to speak with your physician about specific therapeutic options, such as the use of an ACE inhibitor for its renal protective effects. This is a well-established finding in the follow-up and management of patients with diabetes.

JTL

DTQ-20011203215945
Original posting 4 Dec 2001
Posted to Complications

  
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Last Updated: Tuesday April 06, 2010 15:09:28
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