Back to Ask the Diabetes Team Ask the Diabetes Team

From Gainesville, Virginia, USA:

My 11 year old daughter was diagnosed with type 1 diabetes about a month and a half ago, her first cousin (my sister's son) has cystic fibrosis, and the CF doctor suggested that I have my daughter tested for the CF gene. At diagnosis, she presented with all the typical signs (frequent urination, thirst, and weight loss). I have not been tested so I don't know if I'm a carrier. The doctor said that there may be some link between a CF gene carrier and type 1 diabetes. Do you know of any information about this?


Children with cystic fibrosis have a significantly higher risk of diabetes than the general population. There is moreover good evidence that in some of these cases the diabetes has an autoimmune rather than a structural basis and that there is an increased prevalence of high risk HLA genes for autoimmune diabetes in these cases. However, I can find no report of a child with type 1A (autoimmune) diabetes developing cystic fibrosis nor of there being any genetic bias for this. Given this, I do not think that testing your daughter for the CF gene would have any merit.


Original posting 11 Dec 2001
Posted to Genetics and Heredity


  Home Return to Top

Last Updated: Tuesday April 06, 2010 15:09:30
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2017. Comments and Feedback.