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Question: From Denver, Colorado, USA: I have had type 1 diabetes treated with NPH and Humalog for about five months. I also have severe asthma, and, unfortunately, I ended up needing to take prednisone last week on a tapering dose for the next six weeks. I actually got my blood sugars pretty well controlled (My last hemoglobin A1c was 7.7%), but now that I am on the steroids I am seeing my blood sugars elevated more. Can steroids cause this? Answer: Absolutely your higher readings can be due to the use of the prednisone . Prednisone causes glucose to go up for a variety of reasons including breakdown of stored glucose in the muscles and liver (called gluconeogenesis) and can lead to a relative insulin resistance. Not uncommonly, insulin requirements can go while on prednisone --- sometimes dramatically. Please talk with your diabetes team as to how to adjust your insulin -- likely the short-acting Humalog, but they may even want you on Regular for a bit. If asthma is a fairly routine issue for you, ask your doctors if they can consider a medication to inhibit the "triggering" of an asthma attack. This could include: inhaled steroid medications, an inhaled medication called Cromolyn, or a very effective pill called Montelukast (or similar). If your asthma attacks are few and far between, you may not need a routine preventative-type medication. DS [Editor's comment: See Your doctor advises using steroids. SS] DTQ-20011209001116 Original posting 12 Dec 2001 Posted to Other Medications

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Last Updated: Sun Jan 15 12:18:36 2006
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