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Question: From Paso Robles, California, USA: I am 44, normal weight, and walk regularly. I began thyroid therapy over 28 years ago and have been on the same dose of Synthroid [a brand of thyroid hormone replacement] for more than 15 years with normal thyroid tests, but a year I was diagnosed with diabetes treated with insulin, and my current TSH is low. My hemoglobin A1c runs 5.7-6.4%. Three months ago I started taking Prozac and I also take B12 and ferrous gluconate for anemia, which is under control now. My doctor recommended lowering the Synthroid. This is okay, but I want to find out what could influence the dosage. I have no other signs of thyroid disease. Could insulin use cause a change in my TSH levels? Answer: I don't know. Possibly the Synthroid is being better absorbed: did you change time of day or relationship to food? Lab normal values also change over time, and newer, very sensitive TSH tests are widely available now. LD DTQ-20020428232937 Original posting 21 May 2002 Posted to Thyroid

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