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Question: From Turkey: My nephew has had type 1 diabetes since four years of age. He cannot hear without hearing aids, and he cannot see clearly without glasses. My sister and nephew live in Switzerland, and doctors there said that these disorders are connected. Why? My sister is not clear either since they did genetics testing on her and her husband and have found them healthy. I'm so unhappy since I cannot help her, but I'll be extremely happy if you can possibly explain the reason for these diseases. Answer: I'm afraid that I cannot be of much help to you because I don't know enough about your nephew. However, a common association between deafness, blindness and diabetes is congenital rubella (German measles) infection. Other options are very rare genetic syndromes. Genetic testing of your sister and her husband suggests that the doctors are considering such things and you (and they) will have to wait for the results of these tests for more information. KJR Additional comments from Dr. David Schwartz: This child in question (with diabetes, hearing loss and visual problems) may indeed have the conditions connected. Wolfram Syndrome (also called DIDMOAD syndrome for Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, Deafness) is a genetic disorder that is associated with a degree of neurodegeneration. The precise cause is not completely elucidated but has been found to be genetic such that parents would be carriers. A discussion with a clinical geneticist would be very helpful. This disorder can be associated with another hormone imbalance that can lead to increased urination (called Diabetes Insipidus) so if this is indeed the correct diagnosis, it would be prudent to be followed by a pediatric endocrinologist. IDS DTQ-20020722095744 Original posting 22 Aug 2002 Posted to Research: Causes and Prevention

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			Jump to a new section --[ Getting Around ]-- Home Page What's New Privacy Policy Search CWD --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

Last Updated: Sat Mar 11 16:37:20 2006
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