From Orange, California, USA:
My son has both type 1 diabetes and celiac disease. If he had celiac disease first, could the diabetes be complication of that?
What your son has is now called the Autoimmune Polyglandular Syndrome Type II which is a condition in which a number of autoimmune disorders may occur in the same person. In someone who has type 1 diabetes, the most common associated problem is hypothyroidism which should always be tested for as it is so easily remedied. About 8% of this group also have the celiac disease and less than 2% a defect in the adrenal enzyme 21-hydroxylase. For this reason there is also a case for screening for anti 21-hydroxylase antibodies which you might discuss with your son's doctor.
As to which condition comes first, this is hard to answer as they all have a common genetic predisposition, all that can be said is that whilst only 8% of people with type 1A (autoimmune) autoimmune diabetes get celiac disease -- far fewer individuals with celiac disease get diabetes. In addition, there is wide variation both in the components and in which order they present.
Original posting 4 Feb 2003
Posted to Celiac
Last Updated: Tuesday April 06, 2010 15:09:42
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
© Children with Diabetes, Inc. 1995-2015. Comments and Feedback.