From Santa Rosa, California, USA:
Nothing peculiar has been found about the biochemistry of mothers who have children with diabetes. Has this been studied much?
Maternal factors contributing to childhood diabetes have in fact been studied quite a lot and very roughly fall into two groups. The first include genetic factors like the HLA antigen cell surface proteins and off course the diabetic variants due to changes in mitochondrial DNA which are exclusively maternal. Transient neonatal diabetes may rarely be due to a maternal rather than a paternal factor.
What you might call environmental factors also play a part; these include malnutrition, perhaps insufficiency of vitamin D during pregnancy and of course maternal rubeola (German measles). Add to this list whatever series of biochemical changes ultimately lead to type 2 diabetes in both generations.So far as I know though, no simple biochemical parameters in the mother predispose to diabetes in the offspring.
Original posting 17 Mar 2003
Posted to Genetics and Heredity
Last Updated: Tuesday April 06, 2010 15:09:42
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
© Children with Diabetes, Inc. 1995-2016. Comments and Feedback.