Back to Ask the Diabetes Team Ask the Diabetes Team

From San Antonio, Texas, USA:

I heard that people with diabetes have sugar sticking to the walls of their veins and arteries like cholesterol does. Is this true?


Glucose molecules can become transiently attached to a wide variety of proteins in the body. One example familiar to all people with diabetes is the hemoglobin A1c test which measures glucose attachment to hemoglobin. When glucose levels are persistently above normal however, the bonding of glucose to protein is sufficient to distort the function of the protein. In the blood stream this may result in the formation of what are called Advanced Glycation End products or AGEs. These in turn get attached to specific receptors on the lining of blood vessels where they slowly develop an inflammatory process causing the vascular complications of diabetes.


Original posting 23 Jun 2003
Posted to Other


  Home Return to Top

Last Updated: Tuesday April 06, 2010 15:09:46
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2015. Comments and Feedback.