From Tracy, California, USA:
My husband has type 1 diabetes and so do my two year old son and four year old daughter. How often to you hear of or see families in which a parent and both children have type 1 diabetes?
If your husband has type 1A (autoimmune) diabetes, then the chances of any of your offspring developing the same form of diabetes are about 1:20 in each case, but the chances of having two such affected children are only 1:400. This figure however is a simple overall value that does not take into consideration other factors that affect vulnerability to autoimmune problems such as HLA antigen genetic type and the influence of the still little understood environmental factors.
Additional comments from Dr. David Schwartz:Unfortunately, I think the answer to your question is "too often." One of the larger factors for increasing the risk of developing type 1 diabetes is that the father has it.
Additional comments from Dr. Andrea Scaramuzza:I know of at least four families in Italy in which there are two children and a father or mother all of whom have type 1 diabetes.
Original posting 24 Aug 2003
Posted to Genetics and Heredity
Last Updated: Tuesday April 06, 2010 15:09:48
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
© Children with Diabetes, Inc. 1995-2016. Comments and Feedback.