Is Exenatide another novel drug for type 2 diabetes?
Exenatide (synthetic exendin-4), an experimental synthetic peptide, may be an exciting new addition to current treatment for typeá2 diabetes. In phase 3 clinical trials, injections of exenatide (when added to sulfonylureas and/or metformin) enhanced beta cell function, thereby improving blood sugar control and possibly weight loss.
The researchers claim that exenatide is able to increase insulin secretion when needed (when the blood sugar is high), thus decreasing hypoglycemia caused by inappropriate insulin secretion. Although the blood sugar improvement was very encouraging, mild to moderate nausea was a common side effect -- and the medication must be injected. Only time will tell whether this new class of drugs will be a useful addition to the treatment of type 2 diabetes.
Original posting 26 Aug 2003
Posted to Research: Other Research
Last Updated: Tuesday April 06, 2010 15:09:48
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
© Children with Diabetes, Inc. 1995-2017. Comments and Feedback.