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Question: From Ohio, USA: My 17 year old son, who has had type 1 diabetes for 13 years, now has heart disease. Have you heard anything about the saliva of the gila lizard for treatment? Answer: There are indeed ongoing clinical trials of Exenatide (synthetic version of the naturally occurring Exendin-4) in type 2 diabetes, and there are proposals for similar trials in type 1. (See Fineman MS, Bicsak TA, Shen LZ, Taylor K, Gaines E, Varns A, Kim D, Baron AD. Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes. Diabetes Care. 2003 Aug;26(8):2370-7.) One would suppose that its primary effect in enhancing insulin action would not be of special value in established type 1 diabetes, whereas the other action in suppressing inappropriate glucagon secretion might be beneficial, rather on the same principle that [metformin supplements may enhance control in insulin dependent diabetes. It is likely to be several months or years before this new drug is proved of value and becomes available for clinical use. In the meantime, your son needs to do all he can with conventional means to keep in the best possible control. DOB Additional comments from David Mendosa, A Writer on the Web: I have written about this several times. My first article, The Monster Drug, gives some interesting background that you won't find anywhere else. DM Additional comments from Jane Seley, diabetes nurse specialist: We recently answered another question about this. JS DTQ-20030828072850 Original posting 31 Aug 2003 Posted to Other Medications

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			Jump to a new section --[ Getting Around ]-- Home Page What's New Privacy Policy Search CWD --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

Last Updated: Sun Jan 15 12:11:28 2006
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