From St. Paul, Indiana, USA:
Is there any connection between nesidioblastosis and growth hormone deficiency or other bone disorders?
It is very difficult to answer your question without more information on whether this was the adenomatous or diffuse type of nesidioblastosis, or PHHI (Persistent Hypoglycemic Hyperinsulinemia of Infancy) as it is now called, and whether it was treated with diazoxide, octreotide, calcium channel blockers or surgery. I am rather guessing that a subtotal or even total resection of the pancreas was the treatment of choice and that you are concerned with poor growth in height since that time. If this is the case all I can say is that this has been reported; but not yet explained. There is no known connection between infantile hyperinsulinism and bone disorders or with growth after the neonatal period. If there is persistent hypoglycemia this might indicate a need for further surgery. A final possibility would be if your child had been treated over a long period with octreotide either by injection or by pump because somatostain analogues can inhibit the release of growth hormone.
Original posting 30 Dec 2003
Posted to Nesidioblastosis
Last Updated: Tuesday April 06, 2010 15:09:54
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
© Children with Diabetes, Inc. 1995-2016. Comments and Feedback.