From Peoria, Illinois, USA:
I was wondering if when an HbA1c is checked, does it make a difference if the hands are clean (i.e., no residue of sugar)? In our clinic a week ago we have a patient that was amazed his A1c went up and wanted it rechecked. He had just eaten a hamburger and fries from Hardees. When we rechecked it, there was over a 1% point difference. Was this purely a coincidence?
HbA1c assays are not affected by glucose contamination of the skin. However it is important to remember that the 95% confidence limits of the assay even using a reliable instrument like the DCA 2000, and with one person in a unit doing all the assays, can be as high as +/- 8%. This means that a 1% difference between two successive readings on the same person does not necessarily imply significant clinical change or technical error. What it does mean though is that the results always have to be interpreted in relation to an imagined regression line drawn through a significant number of previous results.
Original posting 23 Jan 2004
Posted to A1c, Glycohemoglobin, HgbA1c
Last Updated: Tuesday April 06, 2010 15:09:54
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
© Children with Diabetes, Inc. 1995-2016. Comments and Feedback.