A man, age 45, weight 100 kg (220 pounds), 5 feet, 7 inches tall, had an insulin level 19.2 before a Glucose Tolerance Test (GTT), which was normal. After the GTT, it was 88, which is very high. His blood glucose was 280 mg/dl [15.6 mmol/L] due to the non-utilization of glucose at the time, one hour after GTT. The diabetologist says that this is an obesity oriented situation which is surely reversible after permanent normal weight maintenance. Is this true? What is your expert opinion? Why would there be such a non-utilization of insulin? We think that beta cell function is normal and very good.
It depends on when the glucose of 280 was drawn. If this is at two hours, you have type 2 diabetes as any value greater than 200 mg/dl [11.1 mmol/L] at two hours is considered diabetes. Our model for the development of type 2 diabetes is a combination of both insulin resistance and inappropriate insulin secretion. Individuals can have insulin resistance, but, if they also have elevated glucose, they most surely have an inappropriate insulin secretion as well. My recommendation is that if you have type 2 diabetes, do not wait to induce weight loss before being treated, as the value of 280 mg/dl is very high.
Last Updated: Tuesday April 06, 2010 15:10:00
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
© Children with Diabetes, Inc. 1995-2016. Comments and Feedback.