From Connecticut, USA:
A man, age 31, has had type 1 for 23 years and his wife, 30, has had type 1 for 28 years. How likely is it that their offspring would have type 1? The woman is in excellent health and both have great A1cs. They are seeking a doctor to handle "genetic engineering" to "remove" the afflicted genetic materials. They believe that similar engineering has taken place for other afflictions, but no doctor will discuss it.
There are excellent diabetologists in Connecticut, so, keep searching., There is no known way to remove "bad genetic material" as you propose. It is possible THEORETICALLY, but there is no way to know how to do it. We simply do not know where such genes really reside or how to go about doing this clinically. Perhaps this will be possible in the future.
The risks for two type 1 diabetes parents having a child with diabetes are obviously higher than if only one parent has type 1 diabetes. The current estimate of the risk would be about 10%, about 2 to 4% for a child of a mother with type 1 diabetes, about 3 to 6% for child of a father with type 1 diabetes. Exactly why this difference exists is also not well known. I might suggest that you consider a consultation with not only a diabetologist or obstetrician who works with diabetes but perhaps also a geneticist who can help to answer such questions.
Original posting 16 Jul 2005
Posted to Genetics and Heredity
Last Updated: Tuesday April 06, 2010 15:10:02
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
© Children with Diabetes, Inc. 1995-2016. Comments and Feedback.