Back to Ask the Diabetes Team Ask the Diabetes Team

From England:

I recently had a six month check-up and all seemed fine with my test results. My A1c was 6.5. I have never had an A1c over 8.0 as my type 1 diabetes was diagnosed at a very early stage during pregnancy. However, I have just been asked by my general practitioner to re-submit a urine sample as he has noted that I had elevated levels of protein during the check-up tests. He stressed, however, that there is no evidence of microalbuminuria. Both he and the consultant feel it is probably an erroneous result and just want to double check. I am confused as to the difference between "protein" and "microalbuminuria". If this is not shown to be an erroneous result, what are the possible causes?


Albumin is a specific protein and is a subset of all protein found in urine. The size of urine makes it a good screening test as most albumin should be excluded from the urine. Microalbumin refers to the fact that albumin can be measured at levels before the dipstick urine becomes positive. For instance, albumin is elevated in the urine if it is greater than 30 mg/24 hours on a twenty-four hour specimen. The dipstick urine is positive at albumin levels greater than 300 mg/24 hours. Most of our screening now is done yearly with a random urine sample that measures the ratio of albumin and creatinine in the urine. When a simple dipstick urine for protein is done, false positive results may occur with urinary tract infections or menstrual bleeding (the red blood cells can cause false positives). Positive albumin tests may occur with vigorous exercise, high-protein diet, or with elevated blood sugars. Please ask your physician about testing for microalbumin as this is more specific than total protein and can be measured at levels below the usual protein measurements. It can be easily done with a spot urine test given in the office.


Original posting 11 Sep 2005
Posted to Complications


  Home Return to Top

Last Updated: Tuesday April 06, 2010 15:10:04
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2015. Comments and Feedback.